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Rockville / Maryland / United States
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Adeona Pharmaceuticals is a development-stage, specialty pharmaceutical company that develops orally active, proprietary, late-stage drug candidates for the treatment of autoimmune diseases and central nervous system diseases. It focuses on the development of oral therapies for the treatment of rheumatoid arthritis, multiple sclerosis and age-related macular degeneration. The company manufactures Trimesta, which is as an oral, immunomodulatory and anti-inflammatory agent for the North American market. Adeona Pharmaceuticals also develops a series of rationally designed and small-molecule inhibitors. It additionally offers oral flupirtine that is a centrally active oral therapy for the treatment of fibromyalgia syndrome. The company has operations throughout Michigan.
Rockville / Maryland / United States
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Founded in 1996, Sucampo Pharmaceuticals is a biopharmaceutical company that focuses on the development and commercialization of medicines based on prostones. It develops prostones for the treatment of gastrointestinal, respiratory, vascular and central nervous system diseases and disorders. The company markets AMITIZA in the United States for chronic idiopathic constipation problems in adults. Sucampo Pharmaceuticals operates Sucampo Pharma Europe and Sucampo Pharma subsidiaries. In addition, it offers research and development services and conducts clinical trials. The company also has a sales force that focuses on the institutional and long-term care markets. Sucampo Pharmaceuticals additionally develops and commercializes prostone-based compounds.
Rockville / Maryland / United States
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Rexahn Pharmaceuticals is a clinical stage biopharmaceutical company that focuses on the discovery, development and commercialization of treatment products for various medical conditions, including cancer, central nervous system disorders and sexual dysfunction. The company develops therapies that treat specific disease states. It sells its products under the Archexin, Serdaxin and Zoraxel brands. Archexin is used for the treatment of cancer in glioblastoma, ovary, stomach and pancreas. Its Serdaxin drug treats depression and mood disorders. Zoraxel is a centrally acting sexual dysfunction drug. The company leverages a proprietary nanomedicine research and multitarget aimed ligands platform that is an engine to discover anticancer drugs. Rexahn Pharmaceuticals also provides online information related to various medical disorders and drugs.
Rockville / Maryland / United States
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GlycoMimetics develops novel small molecule therapeutics based upon the roles that carbohydrates play in biological processes. The company believes that carbohydrate mimics, or glycomimetic compounds, represent a new class of drugs. It has identified some compounds with potential therapeutic utility. One class has potential in the treatment of infectious diseases with a novel mechanism of action; the second is a class of anti-inflammatory compounds that have been shown to reduce key measures of inflammation. One of GMI s lead opportunities is to treat or prevent infections caused by Pseudomonas aeruginosa. Its objective in this program is to develop a drug that would be used in conjunction with antibiotics against chronic infections that have failed to respond to antibiotic treatment. The company also has compounds that inhibit selectin binding. Its initial focus in this program is to develop a product to treat acute exacerbations of asthma and chronic obstructive pulmonary disease. GlycoMimetics is headquartered in Gaithersburg, Md.