Santa Fe South High School offers learning options to students in grades 9 through 12. It provides classes in English, math, science, computer technology and social studies. The school administers English as a Learned Language and English Language Learners programs. Santa Fe South High School also offers special education classes to students with learning difficulties. It provides various extracurricular activities, such as art and band. The school is a part of Santa Fe South Schools, which additionally governs Santa Fe South Elementary and Santa Fe South Middle School. Santa Fe South Schools is a full-service charter school district in Oklahoma City.