The University of Texas M. D. Anderson Cancer Center, established in 1941, is one of the leading cancer hospitals in the United States offering diagnosis, treatment and prevention of tumors and cancers. The hospital also operates blood and marrow transplantation center, brain and spine center, and childrens cancer hospital. It has various departments, such as plastic surgery, anesthesiology and pain medicine, behavioral science, dermatological surgery, gastrointestinal, immunology, institutional research, imaging Physics, radiation treatment and urology. It offers clinical trials and research facilities, and also provides educational programs in cancer treatment and prevention. The University of Texas M. D. Anderson Cancer Center is located in Houston.